The phage K lytic enzyme LysK and lysostaphin act synergistically to kill MRSA

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The phage K lytic enzyme LysK and lysostaphin act synergistically to kill MRSA.

LysK is the endolysin from the staphylococcal bacteriophage K, and can digest the cell wall of many staphylococci. Lysostaphin is a bacteriocin secreted by Staphylococcus simulans to kill Staphylococcus aureus. Both LysK and lysostaphin have been shown to lyse methicillin-resistant S. aureus (MRSA). This study describes optimal reaction conditions for the recombinant His-tagged LysK protein (pH...

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ژورنال

عنوان ژورنال: FEMS Microbiology Letters

سال: 2008

ISSN: 0378-1097,1574-6968

DOI: 10.1111/j.1574-6968.2008.01308.x